Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | Q9R069 |
express system | HEK293 |
product tag | C-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-α5. In sickle cell disease, Lu/BCAM is thought to contribute to adhesion of sickle erythrocytes to the vascular wall, especially during vaso-occlusive crises. |
molecular weight | The protein has a predicted MW of 57.95 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Mouse BCAM Protein 2900
$270.00 – $900.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Glu26-Ala541
Mouse BCAM Protein 2900
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-α5. In sickle cell disease, Lu/BCAM is thought to contribute to adhesion of sickle erythrocytes to the vascular wall, especially during vaso-occlusive crises. |
Protein names Basal cell adhesion molecule (B-CAM cell surface glycoprotein) (Lutheran antigen) (CD antigen CD239) |
Gene names Bcam,Bcam Gplu Lu |
Mass 10090Da |
Function Laminin alpha-5 receptor. May mediate intracellular signaling (By similarity). |
Subellular location Membrane ; Single-pass type I membrane protein . |
Target Relevance information above includes information from UniProt accession: Q9R069 |
The UniProt Consortium |
Data
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The purity of Mouse BCAM is greater than 95% as determined by SEC-HPLC. |
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Mouse BCAM on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
Publications
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Protocols
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