Mouse B7-1/CD80 Protein 4061

$165.00 – $550.00

Summary

Expression: HEK293
Pure: Yes (HPLC)
Amino Acid Range: Val38-Asn246

SKU: 4061parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	Q00609
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4.
molecular weight	The protein has a predicted MW of 24.6 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Mouse B7-1/CD80 Protein 4061

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4.
Protein names T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (B7) (CD antigen CD80)
Gene names Cd80,Cd80 B7
Mass 10090Da
Function Involved in the costimulatory signal essential for T lymphocytes activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
Catalytic activity #N/A
Subellular location Membrane; Single-pass type I membrane protein.
Tissues Expressed on activated B-cells, gamma interferon stimulated monocytes and non-circulating B-cell malignancies.
Target Relevance information above includes information from UniProt accession: Q00609
The UniProt Consortium

Data

The purity of Mouse B7-1 is greater than 95% as determined by SEC-HPLC.

Mouse B7-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.