Skip to content

Mouse APRIL/TNFSF13 Protein 3055

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Ala96-Leu241
SKU: 3055parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

Q9D777

express system

HEK293

product tag

C-hFc

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFF R.

molecular weight

The protein has a predicted MW of 43.20 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Mouse APRIL/TNFSF13 Protein 3055

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFF R.
Protein names
Tumor necrosis factor ligand superfamily member 13 (A proliferation-inducing ligand) (APRIL) (CD antigen CD256)
Gene names
Tnfsf13,Tnfsf13 April
Protein family
Tumor necrosis factor family
Mass
10090Da
Function
Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Subellular location
Secreted .
Structure
Homotrimer.
Post-translational modification
The soluble form derives from the membrane form by proteolytic processing.
Target Relevance information above includes information from UniProt accession: Q9D777
The UniProt Consortium

Data

ELISA with Mouse APRIL/TNFSF13 Protein
Immobilized Mouse APRIL, hFc Tag at 5µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Mouse BCMA, His Tag with the EC50 of 3.4ng/ml determined by ELISA.
HPLC of Mouse APRIL/TNFSF13 Protein
The purity of Mouse APRIL is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Mouse APRIL/TNFSF13 Protein
Mouse APRIL on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




pmidtitleauthorscitation

Protocols

relevant to this product

Documents

#
Please enter your product and batch number here to retrieve - product datasheet, SDS, and QC information.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.