Mouse Alkaline Phosphatase (Germ type) /ALPG Protein 2598

$1,050.00

Summary

Expression: HEK293
Pure: Yes (HPLC)
Amino Acid Range: Val19-Ser502

available size

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SKU: 2598parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	P24823
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease.
molecular weight	The protein has a predicted MW of 53.64 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Mouse Alkaline Phosphatase (Germ type) /ALPG Protein 2598

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease.
Protein names Alkaline phosphatase, germ cell type (EC 3.1.3.1) (Alkaline phosphatase 5) (Alkaline phosphatase, placental-like) (Embryonic alkaline phosphatase) (EAP) (Embryonic-type alkaline phosphatase)
Gene names Alpg,Alpg Akp5 Alppl2 Eap
Protein family Alkaline phosphatase family
Mass 10090Da
Function Alkaline phosphatase that can hydrolyze various phosphate compounds.
Catalytic activity BINDING 60; /ligand="Mg(2+)"; /ligand_id="ChEBI:CHEBI:18420"; /evidence="ECO:0000250\|UniProtKB:P05187"; BINDING 60; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="1"; /evidence="ECO:0000250\|UniProtKB:P05187"; BINDING 110; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="1"; /evidence="ECO:0000250\|UniProtKB:P05187"; BINDING 173; /ligand="Mg(2+)"; /ligand_id="ChEBI:CHEBI:18420"; /evidence="ECO:0000250\|UniProtKB:P05187"; BINDING 234; /ligand="Ca(2+)"; /ligand_id="ChEBI:CHEBI:29108"; /evidence="ECO:0000250\|UniProtKB:P05186"; BINDING 287; /ligand="Ca(2+)"; /ligand_id="ChEBI:CHEBI:29108"; /evidence="ECO:0000250\|UniProtKB:P05186"; BINDING 288; /ligand="Ca(2+)"; /ligand_id="ChEBI:CHEBI:29108"; /evidence="ECO:0000250\|UniProtKB:P05186"; BINDING 303; /ligand="Ca(2+)"; /ligand_id="ChEBI:CHEBI:29108"; /evidence="ECO:0000250\|UniProtKB:P05186"; BINDING 329; /ligand="Mg(2+)"; /ligand_id="ChEBI:CHEBI:18420"; /evidence="ECO:0000250\|UniProtKB:P05187"; BINDING 334; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="2"; /evidence="ECO:0000250\|UniProtKB:P05187"; BINDING 338; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="2"; /evidence="ECO:0000250\|UniProtKB:P05187"; BINDING 375; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="1"; /evidence="ECO:0000250\|UniProtKB:P05187"; BINDING 376; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="1"; /evidence="ECO:0000250\|UniProtKB:P05187"; BINDING 450; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="2"; /evidence="ECO:0000250\|UniProtKB:P05187"
Subellular location Cell membrane; Lipid-anchor, GPI-anchor.
Tissues Embryo and testis.
Structure Homodimer.
Target Relevance information above includes information from UniProt accession: P24823
The UniProt Consortium

Data

HPLC of Mouse Alkaline Phosphatase (Germ type) /ALPG Protein

The purity of Mouse Alkaline Phosphatase (Germ type) is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Mouse Alkaline Phosphatase (Germ type) /ALPG Protein

Mouse Alkaline Phosphatase (Germ type) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.