Human TNFRSF19 Protein 5030

$240.00 – $800.00

Summary

Expression: HEK293
Pure: Yes (HPLC)
Amino Acid Range: Glu30-Leu170

SKU: 5030parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	Q9NS68
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	A novel susceptibility gene TNFRSF19, which encodes an orphan member of the TNF receptor superfamily known to be associated with nasopharyngeal carcinoma (NPC) and lung cancer risk. TNFRSF19, a susceptibility gene for nasopharyngeal carcinoma and other cancers, functions as a potent inhibitor of the TGFβ signaling pathway.
molecular weight	The protein has a predicted MW of 16.55 kDa. Due to glycosylation, the protein migrates to 25-40 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Human TNFRSF19 Protein 5030

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
A novel susceptibility gene TNFRSF19, which encodes an orphan member of the TNF receptor superfamily known to be associated with nasopharyngeal carcinoma (NPC) and lung cancer risk. TNFRSF19, a susceptibility gene for nasopharyngeal carcinoma and other cancers, functions as a potent inhibitor of the TGFβ signaling pathway.
Protein names Tumor necrosis factor receptor superfamily member 19 (TRADE) (Toxicity and JNK inducer)
Gene names TNFRSF19,TNFRSF19 TAJ TROY UNQ1888/PRO4333
Mass 9606Da
Function Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.
Subellular location Membrane ; Single-pass type I membrane protein .
Tissues Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes.
Structure Associates with TRAF1, TRAF2, TRAF3 and TRAF5. Interacts with LINGO1.
Target Relevance information above includes information from UniProt accession: Q9NS68
The UniProt Consortium

Data

The purity of Human TNFRSF19 is greater than 95% as determined by SEC-HPLC.

Human TNFRSF19 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.