Human TM4SF1 Protein-VLP 2875

$1,100.00 – $3,800.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Met1-Cys202

SKU: 2875parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	P30408
express system	HEK293
product tag
purity	> 95% as determined by HPLC
background	Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. It is upregulated in several epithelial cancers and is closely associated with poor prognosis.
molecular weight	The target protein has a predicted MW of 21.64 kDa.
available size	100 µg, 500 µg
endotoxin	Less than 1 EU per μg by the LAL method.

Human TM4SF1 Protein-VLP 2875

protein
Size and concentration
100, 500µg and liquid
Form
Liquid
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped with dry ice.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. It is upregulated in several epithelial cancers and is closely associated with poor prognosis.
Protein names
Transmembrane 4 L6 family member 1 (Membrane component chromosome 3 surface marker 1) (Tumor-associated antigen L6)
Gene names
TM4SF1,TM4SF1 M3S1 TAAL6
Protein family
L6 tetraspanin family
Mass
9606Da
Subellular location
Membrane; Multi-pass membrane protein. Note=Colocalizes with SDCBP2 in the apical region of the cell (PubMed:11102519).
Tissues
Highly expressed in lung, breast, colon and ovarian carcinomas. It is also present on some normal cells, endothelial cells in particular.
Structure
Present in high molecular weight complexes in tumor cells. Interacts with SDCBP2 (PubMed:11102519).
Target Relevance information above includes information from UniProt accession: P30408
The UniProt Consortium

Data

Immobilized Human TM4SF1 VLP at 5 µg/ml (100 µl/Well) on the plate. Dose response curve for Anti-TM4SF1 Antibody, hFc Tag with the EC50 of 6.3 ng/ml determined by ELISA.

The purity of Human TM4SF1 VLP is greater than 95% as determined by SEC-HPLC.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.