Human SMOC1 Protein 2341

$300.00 – $1,000.00

Summary

Expression: HEK293
Pure: Yes (SDS-PAGE)
Amino Acid Range: His27-Val434

SKU: 2341parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	Q9H4F8
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE
background	SPARC-related modular calcium binding 1 (SMOC1) represents a vital member of the SPARC matricellular protein family that regulates cell matrix interaction through binding to cell-surface receptors. SMOC1 silencing suppressed the Ang II‑induced myocardial fibrosis of mouse MFBs through affecting the BMP2/Smad signaling pathway.
molecular weight	The protein has a predicted MW of 46.43 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Human SMOC1 Protein 2341

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
SPARC-related modular calcium binding 1 (SMOC1) represents a vital member of the SPARC matricellular protein family that regulates cell matrix interaction through binding to cell-surface receptors. SMOC1 silencing suppressed the Ang IIÃ¢Â€Â‘induced myocardial fibrosis of mouse MFBs through affecting the BMP2/Smad signaling pathway.
Protein names SPARC-related modular calcium-binding protein 1 (Secreted modular calcium-binding protein 1) (SMOC-1)
Gene names SMOC1,SMOC1
Mass 48163Da
Function FUNCTION: Plays essential roles in both eye and limb development. Probable regulator of osteoblast differentiation. {ECO:0000269\|PubMed:20359165, ECO:0000269\|PubMed:21194678, ECO:0000269\|PubMed:21194680}.
Subellular location SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000269\|PubMed:12130637, ECO:0000269\|PubMed:20359165}. Note=In or around the basement membrane.
Tissues TISSUE SPECIFICITY: Widely expressed in many tissues with a strongest signal in ovary. No expression in spleen. {ECO:0000269\|PubMed:12130637}.
Post-translational modification PTM: Glycosylated. {ECO:0000269\|PubMed:12130637}.
Target Relevance information above includes information from UniProt accession: Q9H4F8
The UniProt Consortium

Data

Human SMOC1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.