no metadatahttps://benchmarkantibodies.com/product/human-ror2-ntrkr2-protein-4609/
Skip to content

Human ROR2/NTRKR2 Protein 4609

$270.00$900.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Val34-Gly403
SKU: 4609parent Categories: , Tags: , , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

A1L4F5

express system

HEK293

product tag

C-His-Avi

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain.

molecular weight

The protein has a predicted MW of 44.2 kDa. Due to glycosylation, the protein migrates to 54-58 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human ROR2/NTRKR2 Protein 4609

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain.
Protein names
Receptor tyrosine kinase-like orphan receptor 2
Gene names
ROR2,ROR2
Protein family
Protein kinase superfamily, Tyr protein kinase family, ROR subfamily
Mass
9606Da
Catalytic activity
BINDING 479..487; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000256|PIRSR:PIRSR000624-2"; BINDING 507; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000256|PIRSR:PIRSR000624-2"
Subellular location
SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Target Relevance information above includes information from UniProt accession : A1L4F5
The UniProt Consortium

Data

ELISA with Human ROR2/NTRKR2 Protein
Immobilized Human ROR2, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-ROR2 Antibody, hFc Tag with the EC50 of 3.6ng/ml determined by ELISA.
HPLC of Human ROR2/NTRKR2 Protein
The purity of Human ROR2 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human ROR2/NTRKR2 Protein
Human ROR2 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




pmidtitleauthorscitation

Protocols

relevant to this product

Documents

#
No results found

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.