ELISA with Human ROR2/NTRKR2 Protein 4609

Human ROR2/NTRKR2 Protein 4609

$270.00 – $900.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Val34-Gly403

SKU: 4609parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	A1L4F5
express system	HEK293
product tag	C-His-Avi
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain.
molecular weight	The protein has a predicted MW of 44.2 kDa. Due to glycosylation, the protein migrates to 54-58 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Human ROR2/NTRKR2 Protein 4609

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain.
Protein names Receptor tyrosine kinase-like orphan receptor 2
Gene names ROR2,ROR2
Protein family Protein kinase superfamily, Tyr protein kinase family, ROR subfamily
Mass 9606Da
Catalytic activity BINDING 479..487; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000256\|PIRSR:PIRSR000624-2"; BINDING 507; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000256\|PIRSR:PIRSR000624-2"
Subellular location Membrane ; Single-pass type I membrane protein .
Target Relevance information above includes information from UniProt accession: A1L4F5
The UniProt Consortium

Data

Immobilized Human ROR2, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-ROR2 Antibody, hFc Tag with the EC50 of 3.6ng/ml determined by ELISA.

The purity of Human ROR2 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Human ROR2/NTRKR2 Protein

Human ROR2 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.