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Human Nectin-2/CD112 Protein 2331

$240.00$800.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Gln32-Leu360
SKU: 2331parent Categories: , Tags: , , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

Q92692

express system

HEK293

product tag

No Tag

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth, metastasis and tumor angiogenesis. Nectin-2 expression in ovarian cancer may support tumor cell adhesion, leading to growth and lymph node metastasis. Effect of VEGF on Nectin-2 expression as well as permeability was investigated in HUVEC.

molecular weight

The protein has a predicted MW of 35.54 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human Nectin-2/CD112 Protein 2331

Data

ELISA with Human Nectin-2/CD112 Protein
Immobilized Human Nectin-2, No Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Human PVRIG, mFc Tag with the EC50 of 0.19µg/ml determined by ELISA.
HPLC of Human Nectin-2/CD112 Protein
The purity of Human Nectin-2 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human Nectin-2/CD112 Protein
Human Nectin-2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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