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Human LY6G6D Protein 2306

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Asn20-Ser104
SKU: 2306parent Categories: , Tags: , , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

O95868

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy.

molecular weight

The protein has a predicted MW of 10.20 kDa. Due to glycosylation, the protein migrates to 13-15 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human LY6G6D Protein 2306

Data

ELISA with Human LY6G6D Protein
Immobilized Human LY6G6D, His Tag at 0.2µg/ml (100µl/Well) on the plate. Dose response curve for Anti-LY6G6D Antibody, hFc Tag with the EC50 of 3.9ng/ml determined by ELISA.
HPLC of Human LY6G6D Protein
The purity of Human LY6G6D is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human LY6G6D Protein
Human LY6G6D on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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