SDS-PAGE gel of Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodim 5076

Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein 5076

$375.00 – $1,250.00

Summary

Expression: HEK293
Pure: Yes (SDS-PAGE)
Amino Acid Range: Phe23-Ser1122(ITGA10)acidic tail & Gln21-Asp728(ITGB1)basic tail

available size

Clear

SKU: 5076parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	O75578(ITGA10)&P05556(ITGB1)
express system	HEK293
product tag	C-His
purity	> 90% as determined by Tris-Bis PAGE
background	Alpha 10 beta 1 is currently known as four collagen-binding I domain-containing integrins, the others are namely alpha 1 beta 1, alpha 2 beta 1 and alpha 11 beta 1. α10β1 is likely to be expressed only by a subset of fibroblasts.
molecular weight	The protein has a predicted MW of 125.60 kDa (ITGA10) & 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 140-160 kDa (ITGA10) and 100-130 kDa (ITGB1) based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein 5076

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Alpha 10 beta 1 is currently known as four collagen-binding I domain-containing integrins, the others are namely alpha 1 beta 1, alpha 2 beta 1 and alpha 11 beta 1. α10β1 is likely to be expressed only by a subset of fibroblasts.
Protein names
Integrin alpha-10
Gene names
ITGA10,ITGA10 UNQ468/PRO827
Protein family
Integrin alpha chain family
Mass
127602Da
Function
Integrin alpha-10/beta-1 is a receptor for collagen.
Subellular location
Membrane; Single-pass type I membrane protein.
Tissues
Widely expressed with highest expression in muscle and heart. Found in articular cartilage.
Structure
Heterodimer of an alpha and a beta subunit. Alpha-10 associates with beta-1.
Domain
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo pro
Target Relevance information above includes information from UniProt accession: O75578
The UniProt Consortium

Data

SDS-PAGE gel of Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodim

Human ITGA10&ITGB1 on Tris-Bis PAGE under reduced condition. The purity is greater than 90%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.