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Human IL-1 R9 Protein 2311

$270.00$900.00

Summary

  • Expression: HEK293
  • Pure: Yes (HPLC)
  • Amino Acid Range: Thr17-Lys354
SKU: 2311parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

Q9NP60

express system

HEK293

product tag

C-hFc

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

The interleukin 1 receptor (IL-1R) and the Toll-like receptors (TLRs) are highly homologous innate immune receptors that provide the first line of defense against infection. IL-1R have appeared for functions that do not require IL-1 ligand binding is supported by the case of the orphan receptors IL-1R10 and IL-1R9, which do not have known ligands and that have non-immune functions in the brain.

molecular weight

The protein has a predicted MW of 65.66 kDa. Due to glycosylation, the protein migrates to 75-95 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human IL-1 R9 Protein 2311

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
The interleukin 1 receptor (IL-1R) and the Toll-like receptors (TLRs) are highly homologous innate immune receptors that provide the first line of defense against infection. IL-1R have appeared for functions that do not require IL-1 ligand binding is supported by the case of the orphan receptors IL-1R10 and IL-1R9, which do not have known ligands and that have non-immune functions in the brain.
Protein names
X-linked interleukin-1 receptor accessory protein-like 2 (IL-1 receptor accessory protein-like 2) (IL-1-RAPL-2) (IL-1RAPL-2) (IL1RAPL-2) (EC 3.2.2.6) (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R-9) (IL-1R9) (Three immunoglobulin domain-containing IL-1 receptor-related 1) (TIGIRR-1)
Gene names
IL1RAPL2,IL1RAPL2 IL1R9
Protein family
Interleukin-1 receptor family
Mass
9606Da
Subellular location
Membrane; Single-pass type I membrane protein.
Tissues
Detected at low levels in fetal and adult brain, in particular in the frontal lobe, temporal lobe and cerebellum. Detected at very low levels in skin, liver, fetal ovary and in placenta.
Domain
Th
Target Relevance information above includes information from UniProt accession: Q9NP60
The UniProt Consortium

Data

HPLC of Human IL-1 R9 Protein
The purity of Human IL-1 R9 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human IL-1 R9 Protein
Human IL-1 R9 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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Protocols

relevant to this product

Documents

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