Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | A0A140T913(HLA-A*02:01)&P61769(B2M)&SLYNTVATL |
express system | HEK293 |
product tag | C-His-Avi |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | Gag is the HIV structural precursor protein which is cleaved by viral protease to produce mature infectious viruses. Gag is a polyprotein composed of MA (matrix), CA (capsid), SP1, NC (nucleocapsid), SP2 and p6 domains. The immunodominant HLA-A2-restricted Gag epitope, SLYNTVATL (SL9), is considered to be a poor immunogen because reactivity to it is rare in acute infection despite its paradoxical dominance in patients with chronic infection. |
molecular weight | The protein has a predicted MW of 50.39 kDa. Due to glycosylation, the protein migrates to 52-65 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Human HLA-A*02:01&B2M&HIV Gag (SLYNTVATL) Monomer Protein 2028
$310.00 – $1,125.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and SLYNTVATL peptide
Human HLA-A*02:01&B2M&HIV Gag (SLYNTVATL) Monomer Protein 2028
protein |
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Size and concentration 100, 500µg and liquid |
Form Liquid |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped with dry ice. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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Gag is the HIV structural precursor protein which is cleaved by viral protease to produce mature infectious viruses. Gag is a polyprotein composed of MA (matrix), CA (capsid), SP1, NC (nucleocapsid), SP2 and p6 domains. The immunodominant HLA-A2-restricted Gag epitope, SLYNTVATL (SL9), is considered to be a poor immunogen because reactivity to it is rare in acute infection despite its paradoxical dominance in patients with chronic infection. |
Protein names Major histocompatibility complex, class I, A |
Gene names HLA-A,HLA-A |
Protein family MHC class I family |
Mass 41449Da |
Target Relevance information above includes information from UniProt accession: A0A140T913 |
The UniProt Consortium |
Data
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