Skip to content

Human GDF15 (H202D) Protein 2325

$375.00$1,250.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Ala197-Ile308 (H202D)
SKU: 2325parent Categories: , Tags: , , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

Q99988

express system

HEK293

product tag

N-hFc

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance.

molecular weight

The protein has a predicted MW of 37.88 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human GDF15 (H202D) Protein 2325

Data

ELISA with Human GDF15 (H202D) Protein
Immobilized Human GFRAL, His Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Human GDF15 (H202D), hFc Tag with the EC50 of 4.1ng/ml determined by ELISA.
HPLC of Human GDF15 (H202D) Protein
The purity of Human GDF15 (H202D) is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human GDF15 (H202D) Protein
Human GDF15 (H202D) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




pmidtitleauthorscitation

Protocols

relevant to this product

Documents

#
No results found

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.