Human CDH6/Cadherin-6 Protein 2741

$203.00 – $675.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Thr19 – Ala615

SKU: 2741parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	P55285
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
background	Cadherin 6 (CDH6) is an adhesion molecule localizing to the endometrial luminal epithelial cell surface in the mid-secretory/receptive phase and knockdown of CDH6 in the Ishikawa cells (receptive endometrial epithelial cell line) compromises cell integrity.
molecular weight	The protein has a predicted MW of 67.48 kDa. Due to glycosylation, the protein migrates to 75-95 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1 EU per μg by the LAL method.

Human CDH6/Cadherin-6 Protein 2741

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Cadherin 6 (CDH6) is an adhesion molecule localizing to the endometrial luminal epithelial cell surface in the mid-secretory/receptive phase and knockdown of CDH6 in the Ishikawa cells (receptive endometrial epithelial cell line) compromises cell integrity.
Protein names Cadherin-6 (Kidney cadherin) (K-cadherin)
Gene names CDH6,CDH6
Mass 9606Da
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Catalytic activity #N/A
Subellular location Cell membrane; Single-pass type I membrane protein.
Tissues Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.
Domain Th
Target Relevance information above includes information from UniProt accession: P55285
The UniProt Consortium

Data

ELISA with Human CDH6/Cadherin-6 Protein

Immobilized Human CDH6, His Tag at 2 µg/ml (100 µl/Well) on the plate. Dose response curve for Anti-CDH6 Antibody, Rabbit IgG Tag with the EC50 of 85.1 ng/ml determined by ELISA.

The purity of Human CDH6 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Human CDH6/Cadherin-6 Protein

Human CDH6 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.