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Human CD7 Protein 5216

$300.00$1,000.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Ala26-Pro180
SKU: 5216parent Categories: , Tags: , , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

P09564

express system

HEK293

product tag

C-His-Avi

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

CD7, also known as Leu-9, is an approximately 40 kDa glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily.CD7 is expressed on T cells, NK cells, myeloid progenitor cells, and CD19 B progenitor cells. Among CD8 T cells, the CD7-bright population preferentially contains naïve and memory cells, while more weak expressors are primarily effector cells.

molecular weight

The protein has a predicted MW of 19.3 kDa. Due to glycosylation, the protein migrates to 32-45 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human CD7 Protein 5216

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
CD7, also known as Leu-9, is an approximately 40 kDa glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily.CD7 is expressed on T cells, NK cells , myeloid progenitor cells, and CD19 B progenitor cells. Among CD8 T cells, the CD7-bright population preferentially contains naïve and memory cells, while more weak expressors are primarily effector cells.
Protein names
T-cell antigen CD7 (GP40) (T-cell leukemia antigen) (T-cell surface antigen Leu-9) (TP41) (CD antigen CD7)
Gene names
CD7,CD7
Mass
9606Da
Function
FUNCTION: Not yet known.
Subellular location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
Structure
SUBUNIT: Interacts with SECTM1. {ECO:0000269|PubMed:10652336}.
Target Relevance information above includes information from UniProt accession : P09564
The UniProt Consortium

Data

ELISA with Human CD7 Protein
Immobilized Human CD7, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-CD7 Antibody, hFc Tag with the EC50 3.2ng/ml determined by ELISA (QC Test).
ELISA with Human CD7 Protein
Immobilized Human CD7, His Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Human SECTM1, hFc Tag with the EC50 of 4.2ng/ml determined by ELISA.
HPLC of Human CD7 Protein
The purity of Human CD7 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human CD7 Protein
Human CD7 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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Protocols

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