Human CD30 Ligand/TNFSF8 Protein 4501

$315.00 – $1,050.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Gln63-Asp234

SKU: 4501parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	P32971
express system	HEK293
product tag	N-mFc
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC;
background	CD30 ligand (CD30L)/TNFSF8 is a type II membrane protein belonging to the TNF superfamily. CD30L is expressed on the cell surface of activated T cells, B cells, and monocytes. The protein is also constitutively expressed on granulocytes and medullary thymic epithelial cells.CD30L is a cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.
molecular weight	The protein has a predicted MW of 46.2 kDa. Due to glycosylation, the protein migrates to 62-68 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Human CD30 Ligand/TNFSF8 Protein 4501

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
CD30 ligand (CD30L)/TNFSF8 is a type II membrane protein belonging to the TNF superfamily. CD30L is expressed on the cell surface of activated T cells, B cells, and monocytes. The protein is also constitutively expressed on granulocytes and medullary thymic epithelial cells.CD30L is a cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.
Protein names Tumor necrosis factor ligand superfamily member 8 (CD30 ligand) (CD30-L) (CD antigen CD153)
Gene names TNFSF8,TNFSF8 CD30L CD30LG
Protein family Tumor necrosis factor family
Mass 9606Da
Function Cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.
Subellular location Membrane; Single-pass type II membrane protein.
Structure Homotrimer.
Target Relevance information above includes information from UniProt accession: P32971
The UniProt Consortium

Data

ELISA with Human CD30 Ligand/TNFSF8 Protein

Immobilized Human CD30, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Human CD30 Ligand, mFc Tag with the EC50 of 10.5ng/ml determined by ELISA.

HPLC of Human CD30 Ligand/TNFSF8 Protein

The purity of Human CD30 Ligand is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Human CD30 Ligand/TNFSF8 Protein

Human CD30 Ligand on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.