Human CCL8 Protein 3114

$300.00 – $1,000.00

Summary

Expression: E.coli
Pure: Yes (SDS-PAGE)
Amino Acid Range: Gln24-Pro99

SKU: 3114parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	P80075
express system	E.coli
product tag	No Tag
purity	> 95% as determined by Tris-Bis PAGE
background	C-C motif Chemokine ligand 8 (CCL8) has been found in diseases' pathogenesis. Exogenous CCL8 enhanced the proliferative and migration potential of LE cells and their motility in the environment with its stable concentration.of all the examined factors, chemokine CCL8 participates in the establishment of a proper environment for embryo implantation.
molecular weight	The protein has a predicted MW of 8.91 kDa. The protein migrates to 12-14 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Human CCL8 Protein 3114

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
C-C motif Chemokine ligand 8 (CCL8) has been found in diseases' pathogenesis. Exogenous CCL8 enhanced the proliferative and migration potential of LE cells and their motility in the environment with its stable concentration.of all the examined factors, chemokine CCL8 participates in the establishment of a proper environment for embryo implantation.
Protein names C-C motif chemokine 8 (HC14) (Monocyte chemoattractant protein 2) (Monocyte chemotactic protein 2) (MCP-2) (Small-inducible cytokine A8) [Cleaved into: MCP-2(6-76)]
Gene names CCL8,CCL8 MCP2 SCYA10 SCYA8
Protein family Intercrine beta (chemokine CC) family
Mass 9606Da
Function Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.
Subellular location Secreted.
Tissues Highest expression found in the small intestine and peripheral blood cells. Intermediate levels seen in the heart, placenta, lung, skeletal muscle, thymus, colon, ovary, spinal cord and pancreas. Low levels seen in the brain, liver, spleen and prostate.
Structure Monomer or homodimer; in equilibrium.
Post-translational modification N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Target Relevance information above includes information from UniProt accession: P80075
The UniProt Consortium

Data

Human CCL8 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.