Human CCL7/MCP3 Protein 2946

$315.00 – $1,050.00

Summary

Expression: E.coli
Pure: Yes (HPLC)
Amino Acid Range: Gln24-Leu99

SKU: 2946parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	P80098
express system	E.coli
product tag	N-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	Chemokine C-C motif ligand 7 (CCL7), a member of CC chemokine subfamily, is known to promote the recruitment of many innate immune cell types including monocytes and neutrophils to sites of bacterial and viral infection and eosinophils and basophils to sites of allergic inflammation. CCL7 upregulation has been associated with many inflammatory settings including infection, cardiovascular disease, and the tumor microenvironment.
molecular weight	The protein has a predicted MW of 10.05 kDa. The protein migrates to 14-17 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Human CCL7/MCP3 Protein 2946

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Chemokine C-C motif ligand 7 (CCL7), a member of CC chemokine subfamily, is known to promote the recruitment of many innate immune cell types including monocytes and neutrophils to sites of bacterial and viral infection and eosinophils and basophils to sites of allergic inflammation. CCL7 upregulation has been associated with many inflammatory settings including infection, cardiovascular disease, and the tumor microenvironment.
Protein names C-C motif chemokine 7 (Monocyte chemoattractant protein 3) (Monocyte chemotactic protein 3) (MCP-3) (NC28) (Small-inducible cytokine A7)
Gene names CCL7,CCL7 MCP3 SCYA6 SCYA7
Protein family Intercrine beta (chemokine CC) family
Mass 11200Da
Function Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
Subellular location Secreted.
Structure Monomer. Interacts with TNFAIP6 (via Link domain).
Post-translational modification O-glycosylated.
Target Relevance information above includes information from UniProt accession: P80098
The UniProt Consortium

Data

The purity of Human CCL7 is greater than 95% as determined by SEC-HPLC.

Human CCL7 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.