Human BTN3A2 Protein 2315

$270.00 – $900.00

Summary

Expression: HEK293
Pure: Yes (HPLC)
Amino Acid Range: Gln30-Trp248

SKU: 2315parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	P78410
express system	HEK293
product tag	C-hFc
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	BTN3A2/BT3.2 butyrophilin mRNA expression by tumoral cells was previously identified as a prognostic factor in a small cohort of high grade serous epithelial ovarian cancer (HG-EOC).In conclusion, BT3.2 protein is a potential prognostic biomarker for the identification of HG-EOC patients with better outcome. In contrast, high CD206 /CD68 expression is associated with high risk of disease progression.
molecular weight	The protein has a predicted MW of 50.37 kDa. Due to glycosylation, the protein migrates to 52-65 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Human BTN3A2 Protein 2315

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
BTN3A2/BT3.2 butyrophilin mRNA expression by tumoral cells was previously identified as a prognostic factor in a small cohort of high grade serous epithelial ovarian cancer (HG-EOC).In conclusion, BT3.2 protein is a potential prognostic biomarker for the identification of HG-EOC patients with better outcome. In contrast, high CD206 /CD68 expression is associated with high risk of disease progression.
Protein names Butyrophilin subfamily 3 member A2
Gene names BTN3A2,BTN3A2 BT3.2 BTF3 BTF4
Protein family Immunoglobulin superfamily, BTN/MOG family
Mass 9606Da
Function Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.
Subellular location Cell membrane ; Single-pass type I membrane protein .
Tissues Detected in T-cells and natural killer cells.
Structure Homodimer.
Post-translational modification N-glycosylated.
Target Relevance information above includes information from UniProt accession: P78410
The UniProt Consortium

Data

The purity of Human BTN3A2 is greater than 95% as determined by SEC-HPLC.

Human BTN3A2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.