| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | goat |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | Rat IgA |
| available sizes | 1 mg |
goat anti-Rat IgA-Biotin polyclonal antibody 4229
$191.00
Antibody summary
- Goat polyclonal to Rat IgA-Biotin
- Suitable for: WB,IHC,ICC,ELISA
- Isotype: Whole IgG
- 1 mg
goat anti-Rat IgA-Biotin polyclonal antibody 4229
| antibody |
|---|
| Tested applications WB,IHC,IHC,ICC/IF,ELISA |
| Recommended dilutions Immunoblotting: use at a dilution of 1:1,000-1:200,000. Immunohistochemistry: use at a dilution of 1:250-1:2,500 Immunocytochemistry: use at a dilution of 1:100-1:500 ELISA: use at a dilution of 1:10,000-1:200,000. These are recommended dilutions. End users s |
| Immunogen Rat IgA |
| Size and concentration 1mg and 1 mg/mL |
| Form liquid |
| Storage Instructions This antibody is stable for at least 1 year at 2-8°C. |
| Storage buffer Phosphate Buffered Saline (PBS) containing 0.2% |
| Purity affinity purified |
| Clonality polyclonal |
| Isotype IgG |
| Compatible secondaries donkey anti-goat IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 1689 donkey anti-goat IgG, H&L chain specific, biotin conjugated polyclonal antibody 1699 donkey anti-goat IgG, H&L chain specific, FITC conjugated polyclonal antibody 1704 donkey anti-goat IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1709 donkey anti-goat IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1705 |
| Isotype control Goat polyclonal - Isotype Control |
| target relevance |
|---|
| rat IgA |
| Protein names Immunoglobulin A |
| Alternative names IgA, Alpha immunoglobulin |
| Function IgA protects mucosal surfaces by binding pathogens, toxins, and environmental antigens, thereby preventing their attachment and invasion of host tissues. |
| Subcellular location Secreted; found in blood plasma, saliva, tears, colostrum, breast milk, respiratory secretions, gastrointestinal secretions, and other mucosal fluids. |
| Structure Serum IgA is predominantly monomeric, whereas secretory IgA is typically a dimer composed of two IgA monomers linked by a joining (J) chain and associated with a secretory component. |
| Description Immunoglobulin A (IgA) is the principal antibody isotype found at mucosal surfaces and in secretions. It plays a critical role in mucosal immunity by preventing pathogen attachment, neutralizing toxins, and maintaining host-microbiome homeostasis. |
| Related entities relationship: has_subclass; entity: IgA1 relationship: has_subclass; entity: IgA2 relationship: has_component; entity: J chain relationship: has_component; entity: Secretory component relationship: related_to; entity: Immunoglobulin G relationship: related_to; entity: Immunoglobulin M |
| Keywords Antibody, Immunoglobulin, Mucosal immunity, Adaptive immunity, Host defense |
| Structure Serum IgA is primarily monomeric, while secretory IgA exists mainly as a dimer containing two IgA molecules linked by a J chain and associated with a secretory component. |
| Function IgA protects mucosal surfaces by neutralizing pathogens and toxins, blocking microbial attachment, and contributing to immune exclusion. |
| Subclasses Human IgA consists of two subclasses, IgA1 and IgA2. IgA1 predominates in serum, whereas IgA2 is relatively enriched at mucosal sites. |
| Distribution IgA is abundant in saliva, tears, colostrum, breast milk, respiratory secretions, and gastrointestinal secretions, making it the major antibody of mucosal immunity. |
| Research relevance IgA is widely studied in mucosal immunology, infectious diseases, vaccine responses, gastrointestinal disorders, autoimmune diseases, and allergy research. |
Data
| No results found |
FAQ & Publications
Frequently Asked Questions
What species reactivity does the goat anti-Rat IgA-Biotin polyclonal antibody 4229 exhibit?
This antibody is reactive specifically to Rat IgA.
Which applications has the goat anti-Rat IgA-Biotin polyclonal antibody 4229 been validated for?
It has been tested and recommended for use in Western blotting (WB), immunohistochemistry (IHC), immunocytochemistry/immunofluorescence (ICC/IF), and ELISA.
How should the goat anti-Rat IgA-Biotin polyclonal antibody 4229 be stored to maintain stability?
The antibody is stable for at least one year when stored at 2-8°C in phosphate buffered saline containing 0.2% preservative.
What is the recommended dilution range for using this antibody in ELISA assays?
For ELISA applications, a dilution range of 1:10,000 to 1:200,000 is recommended.
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
| relevant to this product |
|---|
| Western blot IHC ICC |
Documents
| Batch Number | QC File | SDS |
|---|---|---|
| To view batch-specific Safety Datasheets and Quality Certificates associated with your account, please Log In. | ||
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