| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | goat |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | Human IgG Fc specific |
| available sizes | 1 mg |
goat anti-Human IgG Fc Specific polyclonal antibody 5917
$215.00
Antibody summary
- Goat polyclonal to Human IgG Fc Specific
- Suitable for: WB,IHC,ICC,ELISA
- Isotype: Whole IgG
- 1 mg
goat anti-Human IgG Fc Specific polyclonal antibody 5917
| antibody |
|---|
| Tested applications WB,IHC,IHC,ICC/IF,ELISA |
| Recommended dilutions ELISA: Coating: 1:100-1:500,Primary: 1:1,000-1:30,000 Western Blot - Colorimetric: 1:1,000-1:10,000, Chemiluminescent: 1:1,000-1:30,000 Immunohistochemistry: 1:200-1:2,000 Immunocytochemistry: 1:200-1:2,000 These are recommended dilutions only. End user should |
| Immunogen Human IgG Fc fragment. |
| Size and concentration 1mg and 1 mg/mL |
| Form liquid |
| Storage Instructions Store at 2-8°C. Expires 2 years from date of receipt. |
| Storage buffer Phosphate Buffered Saline (PBS) containing 0.09 |
| Purity peptide affinity purification |
| Clonality polyclonal |
| Isotype IgG |
| Compatible secondaries donkey anti-goat IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 1689 donkey anti-goat IgG, H&L chain specific, biotin conjugated polyclonal antibody 1699 donkey anti-goat IgG, H&L chain specific, FITC conjugated polyclonal antibody 1704 donkey anti-goat IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1709 donkey anti-goat IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1705 |
| Isotype control Goat polyclonal - Isotype Control |
| target relevance |
|---|
| human IgG |
| Protein names Immunoglobulin G |
| Alternative names IgG, Gamma immunoglobulin, Gamma globulin |
| Function IgG antibodies bind antigens with high specificity and mediate immune protection through pathogen neutralization, opsonization, complement activation, antibody-dependent cellular cytotoxicity (ADCC), and immune complex formation. |
| Subcellular location Secreted; found predominantly in blood plasma, lymph, extracellular fluids, and tissues. |
| Structure IgG is a heterotetrameric glycoprotein composed of two identical gamma heavy chains and two identical light chains linked by disulfide bonds. The molecule contains two antigen-binding Fab regions and one Fc region. |
| Description Immunoglobulin G (IgG) is the most abundant antibody isotype in human serum and extracellular fluids. It plays a central role in adaptive immunity by recognizing antigens, neutralizing pathogens, activating effector mechanisms, and providing long-term immune protection. |
| Related entities relationship: has_subclass; entity: IgG1 relationship: has_subclass; entity: IgG2 relationship: has_subclass; entity: IgG3 relationship: has_subclass; entity: IgG4 relationship: related_to; entity: IgA relationship: related_to; entity: IgM relationship: related_to; entity: IgE relationship: related_to; entity: IgD |
| Keywords Antibody, Immunoglobulin, Adaptive immunity, Humoral immunity, Complement activation |
| Structure IgG is composed of two gamma heavy chains and two light chains arranged into a Y-shaped antibody molecule containing Fab and Fc regions. |
| Function IgG mediates antigen recognition, pathogen neutralization, opsonization, complement activation, and Fc receptor-dependent immune responses. |
| Subclasses Human IgG is divided into four subclasses: IgG1, IgG2, IgG3, and IgG4, each possessing distinct effector functions and antigen preferences. |
| Distribution IgG is the most abundant immunoglobulin in serum and extracellular fluids and is the dominant antibody during secondary immune responses. |
| Research relevance IgG is widely studied in immunology, infectious disease, autoimmunity, oncology, vaccine development, and therapeutic antibody research. |
Data
| No results found |
FAQ & Publications
Frequently Asked Questions
What species does the goat anti-Human IgG Fc Specific polyclonal antibody 5917 specifically recognize?
This antibody specifically recognizes the Fc region of Human IgG.
Which experimental applications is this antibody validated for?
The antibody has been tested and is suitable for Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC/IF), and ELISA applications.
How should the goat anti-Human IgG Fc Specific polyclonal antibody 5917 be stored to maintain stability?
The antibody should be stored at 2-8°C and is stable for up to 2 years from the date of receipt.
What is the recommended dilution range for using this antibody in ELISA assays?
For ELISA, recommended dilutions are 1:100 to 1:500 for coating and 1:1,000 to 1:30,000 for primary antibody incubation.
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
| relevant to this product |
|---|
| Western blot IHC ICC |
Documents
| Batch Number | QC File | SDS |
|---|---|---|
| To view batch-specific Safety Datasheets and Quality Certificates associated with your account, please Log In. | ||
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