| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | goat |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | Human IgAα Chain specific |
| available sizes | 1 mg |
goat anti-Human IgA, α Chain Specific-Biotin polyclonal antibody 2233
$270.00
Antibody summary
- Goat polyclonal to Human IgA, α Chain Specific-Biotin
- Suitable for: WB,IHC,ICC,ELISA
- Isotype: Whole IgG
- 1 mg
goat anti-Human IgA, α Chain Specific-Biotin polyclonal antibody 2233
| antibody |
|---|
| Tested applications WB,IHC,IHC,ICC/IF,ELISA |
| Recommended dilutions ELISA: 1:10,000-1:100,000 with enzyme-conjugated streptavidin Western Blot: 1:10,000-1:100,000 with enzyme-conjugated streptavidin . Prepare working dilutions immediately before use. These are recommended dilutions. User should determine optimal dilutions for their applicat |
| Immunogen Human IgA |
| Size and concentration 1mg and 1 mg/mL |
| Form liquid |
| Storage Instructions Store at 2-8°C. Shelf life is one (1) year from date of receipt. |
| Storage buffer Phosphate Buffered Saline (PBS) containing 0.2% |
| Purity peptide affinity purification |
| Clonality polyclonal |
| Isotype IgG |
| Compatible secondaries donkey anti-goat IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 1689 donkey anti-goat IgG, H&L chain specific, biotin conjugated polyclonal antibody 1699 donkey anti-goat IgG, H&L chain specific, FITC conjugated polyclonal antibody 1704 donkey anti-goat IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1709 donkey anti-goat IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1705 |
| Isotype control Goat polyclonal - Isotype Control |
| target relevance |
|---|
| human IgA |
| Protein names Immunoglobulin A |
| Alternative names IgA, Alpha immunoglobulin |
| Function IgA protects mucosal surfaces by binding pathogens, toxins, and environmental antigens, thereby preventing their attachment and invasion of host tissues. |
| Subcellular location Secreted; found in blood plasma, saliva, tears, colostrum, breast milk, respiratory secretions, gastrointestinal secretions, and other mucosal fluids. |
| Structure Serum IgA is predominantly monomeric, whereas secretory IgA is typically a dimer composed of two IgA monomers linked by a joining (J) chain and associated with a secretory component. |
| Description Immunoglobulin A (IgA) is the principal antibody isotype found at mucosal surfaces and in secretions. It plays a critical role in mucosal immunity by preventing pathogen attachment, neutralizing toxins, and maintaining host-microbiome homeostasis. |
| Related entities relationship: has_subclass; entity: IgA1 relationship: has_subclass; entity: IgA2 relationship: has_component; entity: J chain relationship: has_component; entity: Secretory component relationship: related_to; entity: Immunoglobulin G relationship: related_to; entity: Immunoglobulin M |
| Keywords Antibody, Immunoglobulin, Mucosal immunity, Adaptive immunity, Host defense |
| Structure Serum IgA is primarily monomeric, while secretory IgA exists mainly as a dimer containing two IgA molecules linked by a J chain and associated with a secretory component. |
| Function IgA protects mucosal surfaces by neutralizing pathogens and toxins, blocking microbial attachment, and contributing to immune exclusion. |
| Subclasses Human IgA consists of two subclasses, IgA1 and IgA2. IgA1 predominates in serum, whereas IgA2 is relatively enriched at mucosal sites. |
| Distribution IgA is abundant in saliva, tears, colostrum, breast milk, respiratory secretions, and gastrointestinal secretions, making it the major antibody of mucosal immunity. |
| Research relevance IgA is widely studied in mucosal immunology, infectious diseases, vaccine responses, gastrointestinal disorders, autoimmune diseases, and allergy research. |
Data
| No results found |
FAQ & Publications
Frequently Asked Questions
What species is the goat anti-Human IgA, α Chain Specific-Biotin antibody reactive with?
This antibody is specific for human IgA α chain and is reactive with human IgA.
Which applications has this antibody been tested and recommended for use?
The antibody has been tested and is suitable for Western blot (WB), immunohistochemistry (IHC), immunocytochemistry/immunofluorescence (ICC/IF), and ELISA applications.
How should the goat anti-Human IgA, α Chain Specific-Biotin antibody be stored to maintain stability?
Store the antibody at 2-8°C. The shelf life is one year from the date of receipt.
What is the recommended dilution range when using this antibody for ELISA and Western blot assays?
For ELISA and Western blot, the recommended dilution range is from 1:10,000 to 1:100,000 when used with enzyme-conjugated streptavidin. Working dilutions should be prepared immediately before use.
What is the immunogen used to raise this goat polyclonal antibody?
The immunogen for this antibody is human IgA.
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
| relevant to this product |
|---|
| Western blot IHC ICC |
Documents
| Batch Number | QC File | SDS |
|---|---|---|
| To view batch-specific Safety Datasheets and Quality Certificates associated with your account, please Log In. | ||
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