FITC-Compatible Human BCMA/TNFRSF17 Protein 2500

$900.00 – $2,000.00

Summary

Expression: HEK293
Active: Yes (cell based assay)
Amino Acid Range: Met1-Ala54

available size

Clear

SKU: 2500parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	Q02223
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF).
molecular weight	The protein has a predicted MW of 35.9 kDa. Due to glycosylation, the protein migrates to 37-48 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

FITC-Compatible Human BCMA/TNFRSF17 Protein 2500

protein

Size and concentration 100, 500µg and liquid
Form Liquid
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped with dry ice.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF).
Protein names Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein) (CD antigen CD269)
Gene names TNFRSF17,TNFRSF17 BCM BCMA
Mass 20165Da
Function Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Subellular location Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Note=Perinuclear Golgi-like structures.
Tissues Expressed in mature B-cells, but not in T-cells or monocytes.
Structure Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6.
Domain TOPO_DOM 1
Target Relevance information above includes information from UniProt accession: Q02223
The UniProt Consortium

Data

Cell based assay with FITC-Compatible Human BCMA/TNFRSF17 Protein

Use 100 µl FITC-Compatible Human BCMA (1 µg/ml) to detect the positive rate of 1-10⁶ anti-BCMA CAR cells. Non-transfected 293T cells and FITC-Labeled irrelevant protein (100 µl, 1 µg/ml) were served as negative control.

HPLC of FITC-Compatible Human BCMA/TNFRSF17 Protein

The purity of FITC-Compatible Human BCMA is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of FITC-Compatible Human BCMA/TNFRSF17 Protein

FITC-Compatible Human BCMA on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.