Cynomolgus ROR2/NTRKR2 Protein 2541

$315.00 – $1,050.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Glu34-Met402

SKU: 2541parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	A0A7N9D5U8
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain.
molecular weight	The protein has a predicted MW of 42.29 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Cynomolgus ROR2/NTRKR2 Protein 2541

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain.
Protein names
Receptor tyrosine kinase like orphan receptor 2
Gene names
ROR2,ROR2
Protein family
Protein kinase superfamily, Tyr protein kinase family, ROR subfamily
Mass
9541Da
Catalytic activity
BINDING 479..487; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000256|PIRSR:PIRSR000624-2"; BINDING 507; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000256|PIRSR:PIRSR000624-2"
Subellular location
Membrane ; Single-pass type I membrane protein .
Target Relevance information above includes information from UniProt accession: A0A7N9D5U8
The UniProt Consortium

Data

ELISA with Cynomolgus ROR2/NTRKR2 Protein

Immobilized Cynomolgus ROR2, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-ROR2 Antibody, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA.

The purity of Cynomolgus ROR2 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Cynomolgus ROR2/NTRKR2 Protein

Cynomolgus ROR2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.