Cynomolgus/Rhesus macaque TNFSF15 Protein 2657

$315.00 – $1,050.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Leu72-Leu251

available size

Clear

SKU: 2657parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	A0A2K5UA22
express system	HEK293
product tag	N-His
purity	> 90% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2.
molecular weight	The protein has a predicted MW of 21.52 kDa. Due to glycosylation, the protein migrates to 25-35 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Cynomolgus/Rhesus macaque TNFSF15 Protein 2657

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2.
Protein names
Vascular endothelial cell growth inhibitor
Protein family
Tumor necrosis factor family
Mass
9541Da
Target Relevance information above includes information from UniProt accession: A0A2K5UA22
The UniProt Consortium

Data

SPR with Cynomolgus/Rhesus macaque TNFSF15 Protein

Mouse DR3, His Tag immobilized on CM5 Chip can bind Cynomolgus/Rhesus macaque TNFSF15, His Tag with an affinity constant of 11.70 nM as determined in SPR assay (Biacore T200).

ELISA with Cynomolgus/Rhesus macaque TNFSF15 Protein

Immobilized Cynomolgus/Rhesus macaque TNFSF15, His Tag at 2µg/ml (100µl/Well) on the plate. Dose response curve for Anti-TNFSF15 Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA (QC Test).

HPLC of Cynomolgus/Rhesus macaque TNFSF15 Protein

The purity of Cynomolgus/Rhesus macaque TNFSF15 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Cynomolgus/Rhesus macaque TNFSF15 Protein

Cynomolgus/Rhesus macaque TNFSF15 on Tris-Bis PAGE under reduced condition. The purity is greater than 90%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.