Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | XP_005545179 |
express system | HEK293 |
product tag | C-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. |
molecular weight | The protein has a predicted MW of 21.84 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Cynomolgus/Rhesus macaque OX40/TNFRSF4/CD134 Protein 2140
$203.00 – $675.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Lys28-Ala214
Cynomolgus/Rhesus macaque OX40/TNFRSF4/CD134 Protein 2140
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. |
Protein names Tumor necrosis factor receptor superfamily member 4 (ACT35 antigen) (OX40L receptor) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD antigen CD134) |
Gene names TNFRSF4,TNFRSF4 TXGP1L |
Mass 9606Da |
Function Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity.; (Microbial infection) Acts as a receptor for human herpesvirus 6B/HHV-6B. |
Subellular location Membrane; Single-pass type I membrane protein. |
Structure Interacts with TRAF2, TRAF3 and TRAF5.; (Microbial infection) Interacts with Human herpesvirus 6B/HHV-6B gQ1:gQ2 proteins. |
Target Relevance information above includes information from UniProt accession: P43489 |
The UniProt Consortium |
Data
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The purity of Cynomolgus/Rhesus macaque OX40 is greater than 95% as determined by SEC-HPLC. |
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Cynomolgus/Rhesus macaque OX40 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
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