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Cynomolgus PLAU/uPA Protein (active form) 3149 – benchmark antibodies Cynomolgus PLAU/uPA Protein (active form) 3149
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SPR with Cynomolgus PLAU/uPA Protein (active form) 3149
SPR with Cynomolgus PLAU/uPA Protein (active form) 3149

Cynomolgus PLAU/uPA Protein (active form) 3149

$315.00 – $1,050.00

Summary

  • Expression: HEK293
  • Active: Yes (catalytic)
  • Amino Acid Range: Ser21-Leu430
SKU: 3149parent Categories: , Tag:
Weight 1 lbs
Dimensions 9 × 5 × 2 in
accession

A0A2K5WND1
express system

HEK293
product tag

C-His
purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background

Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
molecular weight

The protein has a predicted MW of 47.23 kDa. Due to protein lysis and glycosylation, the protein migrates to 23-25 kDa (long chain A), 35-40 kDa (chain B) and 50-60 kDa (long chain A&chain B) based on Tris-Bis PAGE result.
available size

100 µg, 500 µg
endotoxin

Less than 1EU per μg by the LAL method.

Cynomolgus PLAU/uPA Protein (active form) 3149
protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
Protein names
Urokinase-type plasminogen activator (EC 3.4.21.73)
Gene names
PLAU,PLAU
Mass
9541Da
Function
Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.
Target Relevance information above includes information from UniProt accession: A0A2K5WND1
The UniProt Consortium

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