Cynomolgus IL-22 Protein 3146

$315.00 – $1,050.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Ala34-Ile179

SKU: 3146parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	G7PHZ7
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production.
molecular weight	The protein has a predicted MW of 17.69 kDa. Due to glycosylation, the protein migrates to 32-42 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Cynomolgus IL-22 Protein 3146

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production.
Protein names Interleukin 22
Gene names IL22,IL22
Protein family IL-10 family
Mass 9541Da
Subellular location Secreted .
Target Relevance information above includes information from UniProt accession: G7PHZ7
The UniProt Consortium

Data

Cynomolgus IL-22R alpha 1, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-22, His Tag with an affinity constant of 60.21 nM as determined in SPR assay (Biacore T200).

Immobilized Cynomolgus IL-22, His Tag at 5µg/ml (100µl/Well) on the plate. Dose response curve for Human IL-22R alpha 1, hFc Tag with the EC50 of 0.17µg/ml determined by ELISA (QC Test).

The purity of Cynomolgus IL-22 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Cynomolgus IL-22 Protein

Cynomolgus IL-22 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.