Cynomolgus GPRC5D Protein-VLP 2710

$1,100.00 – $3,800.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Met1-Cys300

SKU: 2710parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	A0A2K5W6I7
express system	HEK293
product tag
purity	> 95% as determined by HPLC
background	Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.
molecular weight	The target protein has a predicted MW of 35.10 kDa.
available size	100 µg, 500 µg
endotoxin	Less than 1 EU per μg by the LAL method.

Cynomolgus GPRC5D Protein-VLP 2710

protein
Size and concentration
100, 500µg and liquid
Form
Liquid
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped with dry ice.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.
Protein names
G protein-coupled receptor class C group 5 member D
Gene names
GPRC5D,GPRC5D
Mass
9541Da
Subellular location
Cell membrane ; Multi-pass membrane protein. Membrane ; Multi-pass membrane protein .
Target Relevance information above includes information from UniProt accession: A0A2K5W6I7
The UniProt Consortium

Data

ELISA with Cynomolgus GPRC5D Protein-VLP

Immobilized Cynomolgus GPRC5D VLP (100 µl/Well) at 5 µg/ml (100 µl/Well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 6.91 µg/ml determined by ELISA.

The purity of Cynomolgus GPRC5D VLP is greater than 95% as determined by SEC-HPLC.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.