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Cynomolgus GAS6 Protein 3132

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Ala31-Ala637
SKU: 3132parent Categories: , Tag:
Weight 1 lbs
Dimensions 9 × 5 × 2 in
accession

A0A2K5VGX7

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM).

molecular weight

The protein has a predicted MW of 68.55 kDa. Due to glycosylation, the protein migrates to 69-74 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Cynomolgus GAS6 Protein 3132

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM).
Protein names
Growth arrest specific 6
Gene names
GAS6,GAS6
Mass
9541Da
Subellular location
Secreted .
Target Relevance information above includes information from UniProt accession: A0A2K5VGX7
The UniProt Consortium

Data

SPR with Cynomolgus GAS6 Protein
Cynomolgus Axl, His Tag immobilized on CM5 Chip can bind Cynomolgus GAS6, His Tag with an affinity constant of 1.70 nM as determined in SPR assay (Biacore T200).
ELISA with Cynomolgus GAS6 Protein
Immobilized Cynomolgus GAS6, His Tag at 2µg/ml (100µl/Well) on the plate. Dose response curve for Anti-Gas6 Antibody, hFc Tag with the EC50 of 26.1ng/ml determined by ELISA (QC Test).
HPLC of Cynomolgus GAS6 Protein
The purity of Cynomolgus GAS6 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Cynomolgus GAS6 Protein
Cynomolgus GAS6 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Publications

pmid title authors citation
We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product

Documents

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