Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | A0A2K5W6J6 |
express system | HEK293 |
product tag | C-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 is differentially expressed in gastric cancer. EphA5 may therefore be a potential therapeutic target and may have clinical utility as a marker for lymph node metastasis in gastric cancer. |
molecular weight | The protein has a predicted MW of 61.73 kDa. Due to glycosylation, the protein migrates to 70-75kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Cynomolgus EPHA5 Protein 3057
$315.00 – $1,050.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Pro25-Gln572
Cynomolgus EPHA5 Protein 3057
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 is differentially expressed in gastric cancer. EphA5 may therefore be a potential therapeutic target and may have clinical utility as a marker for lymph node metastasis in gastric cancer. |
Protein names receptor protein-tyrosine kinase (EC 2.7.10.1) |
Gene names EPHA5,EPHA5 |
Mass 9541Da |
Catalytic activity BINDING 660..668; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000256|PIRSR:PIRSR000666-2"; BINDING 686; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000256|PIRSR:PIRSR000666-2, ECO:0000256|PROSITE-ProRule:PRU10141" |
Subellular location Membrane ; Single-pass type I membrane protein . |
Target Relevance information above includes information from UniProt accession: A0A2K5W6J6 |
The UniProt Consortium |
Data
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The purity of Cynomolgus EPHA5 is greater than 95% as determined by SEC-HPLC. |
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Cynomolgus EPHA5 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
Publications
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Protocols
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