Cynomolgus DR6/TNFRSF21 Protein 3124

$270.00 – $900.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Gln42-His349

SKU: 3124parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	A0A2K5VIJ8
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	beta-amyloid precursor protein (APP) and death receptor 6 (DR6, also known as TNFRSF21) activate a widespread caspase-dependent self-destruction program. DR6 is broadly expressed by developing neurons, and is required for normal cell body death and axonal pruning both in vivo and after trophic-factor deprivation in vitro.DR6 is activated locally by an inactive surface ligand(s) that is released in an active form after trophic-factor deprivation.
molecular weight	The protein has a predicted MW of 34.50 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Cynomolgus DR6/TNFRSF21 Protein 3124

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
beta-amyloid precursor protein (APP) and death receptor 6 (DR6, also known as TNFRSF21) activate a widespread caspase-dependent self-destruction program. DR6 is broadly expressed by developing neurons, and is required for normal cell body death and axonal pruning both in vivo and after trophic-factor deprivation in vitro.DR6 is activated locally by an inactive surface ligand(s) that is released in an active form after trophic-factor deprivation.
Protein names
TNF receptor superfamily member 21
Gene names
TNFRSF21,TNFRSF21
Mass
9541Da
Target Relevance information above includes information from UniProt accession: A0A2K5VIJ8
The UniProt Consortium

Data

ELISA with Cynomolgus DR6/TNFRSF21 Protein

Immobilized Cynomolgus DR6, His Tag at 0.2µg/ml (100µl/Well) on the plate. Dose response curve for Anti-DR6 Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA.

The purity of Cynomolgus DR6 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Cynomolgus DR6/TNFRSF21 Protein

Cynomolgus DR6 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.