Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta Protein 2474

$300.00 – $1,000.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Gln22-Asp117(CD3E) & Phe22-Ala105(CD3D)

available size

Clear

SKU: 2474parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	Q95LI5.2(CD3E)&Q95LI8(CD3D)
express system	HEK293
product tag	C-His-Flag
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	T-cell surface glycoprotein CD3 epsilon&CD3 delta chain, also known as CD3E & CD3D, are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
molecular weight	The protein has a predicted MW of 11.93 kDa (CD3E) and 10.55 kDa (CD3D). Due to glycosylation, the protein migrates to 13-20 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta Protein 2474

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

No information

target relevance

Data

ELISA with Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta Protein

Immobilized Cynomolgus CD3E&CD3D, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-CD3 Antibody, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA.

HPLC of Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta Protein

The purity of Cynomolgus CD3E&CD3D is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta Protein

Cynomolgus CD3E&CD3D on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.