Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | Q4R6B4 |
express system | HEK293 |
product tag | C-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | CD36, alternatively known as platelet membrane glycoprotein IV (GPIV), GPIIIb, thrombospondin receptor, collagen receptor, fatty acid translocase (FAT), and scavenger receptor class B, member 3 (SR-B3), is an integral membrane glycoprotein that has multiple physiological functions.CD36 is a multifunctional glycoprotein that acts as receptor for a broad range of ligands. Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyloid-beta as well as of lipidic nature such as oxidized low-density lipoprotein (oxLDL), anionic phospholipids, long-chain fatty acids and bacterial diacylated lipopeptides. |
molecular weight | The protein has a predicted MW of 47.67 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Cynomolgus CD36/SR-B3 Protein 3067
$315.00 – $1,050.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Gly30-Asn439
Cynomolgus CD36/SR-B3 Protein 3067
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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CD36, alternatively known as platelet membrane glycoprotein IV (GPIV), GPIIIb, thrombospondin receptor, collagen receptor, fatty acid translocase (FAT), and scavenger receptor class B, member 3 (SR-B3), is an integral membrane glycoprotein that has multiple physiological functions.CD36 is a multifunctional glycoprotein that acts as receptor for a broad range of ligands. Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyloid-beta as well as of lipidic nature such as oxidized low-density lipoprotein (oxLDL), anionic phospholipids, long-chain fatty acids and bacterial diacylated lipopeptides. |
Protein names Platelet glycoprotein 4 (Glycoprotein IIIb) (PAS IV) (PAS-4) (Platelet glycoprotein IV) |
Gene names CD36,CD36 |
Protein family CD36 family |
Mass 53041Da |
Catalytic activity CATALYTIC ACTIVITY: Reaction=(9Z)-octadecenoate(out) = (9Z)-octadecenoate(in); Xref=Rhea:RHEA:33655, ChEBI:CHEBI:30823; Evidence={ECO:0000256|ARBA:ARBA00000626}; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:33656; Evidence={ECO:0000256|ARBA:ARBA00000626}; CATALYTIC ACTIVITY: Reaction=(9Z,12Z)-octadecadienoate(out) = (9Z,12Z)-octadecadienoate(in); Xref=Rhea:RHEA:45264, ChEBI:CHEBI:30245; Evidence={ECO:0000256|ARBA:ARBA00000542}; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:45265; Evidence={ECO:0000256|ARBA:ARBA00000542}; CATALYTIC ACTIVITY: Reaction=butanoate(out) = butanoate(in); Xref=Rhea:RHEA:45248, ChEBI:CHEBI:17968; Evidence={ECO:0000256|ARBA:ARBA00001892}; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:45249; Evidence={ECO:0000256|ARBA:ARBA00001892}; CATALYTIC ACTIVITY: Reaction=hexadecanoate(out) = hexadecanoate(in); Xref=Rhea:RHEA:45256, ChEBI:CHEBI:7896; Evidence={ECO:0000256|ARBA:ARBA00000934}; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:45257; Evidence={ECO:0000256|ARBA:ARBA00000934}; CATALYTIC ACTIVITY: Reaction=tetracosanoate(out) = tetracosanoate(in); Xref=Rhea:RHEA:45260, ChEBI:CHEBI:31014; Evidence={ECO:0000256|ARBA:ARBA00023949}; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:45261; Evidence={ECO:0000256|ARBA:ARBA00023949}; CATALYTIC ACTIVITY: Reaction=tetradecanoate(out) = tetradecanoate(in); Xref=Rhea:RHEA:45252, ChEBI:CHEBI:30807; Evidence={ECO:0000256|ARBA:ARBA00000996}; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:45253; Evidence={ECO:0000256|ARBA:ARBA00000996}; |
Subellular location SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000256|ARBA:ARBA00004221}. Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}. Membrane raft {ECO:0000256|ARBA:ARBA00004285}. |
Target Relevance information above includes information from UniProt accession: Q4R6B4 |
The UniProt Consortium |
Data
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The purity of Cynomolgus CD36 is greater than 95% as determined by SEC-HPLC. |
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Cynomolgus CD36 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
Publications
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