Cynomolgus ANGPTL3/Angiopoietin-like 3 Protein 2719

$315.00 – $1,050.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Ser17-Glu460

available size

Clear

SKU: 2719parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	A0A2K5UDC5
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake.
molecular weight	The protein has a predicted MW of 52.86 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Cynomolgus ANGPTL3/Angiopoietin-like 3 Protein 2719

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake.
Protein names Angiopoietin like 3
Gene names ANGPTL3,ANGPTL3
Mass 9541Da
Target Relevance information above includes information from UniProt accession: A0A2K5UDC5
The UniProt Consortium

Data

ELISA with Cynomolgus ANGPTL3/Angiopoietin-like 3 Protein

Immobilized Cynomolgus ANGPTL3, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-ANGPTL3 Antibody, hFc Tag with the EC50 of 10.1ng/ml determined by ELISA.

HPLC of Cynomolgus ANGPTL3/Angiopoietin-like 3 Protein

The purity of Cynomolgus ANGPTL3 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Cynomolgus ANGPTL3/Angiopoietin-like 3 Protein

Cynomolgus ANGPTL3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.