Cynomolgus ADAM9 Protein 2774

$315.00 – $1,050.00

Summary

Expression: HEK293
Active: Yes (catalytic)
Amino Acid Range: Ala29-Gly698

SKU: 2774parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	A0A2K5X4X8
express system	HEK293
product tag	C-His
purity	> 90% as determined by Tris-Bis PAGE;> 90% as determined by HPLC
background	A disintegrin and metalloproteinase 9 (ADAM9) is a member of the transmembrane ADAM family. It is expressed in different types of solid cancer and promotes tumor invasiveness. ADAM9 may be a prognostic marker for vestibular schwannomas (VS), and ADAM9 inhibition might have the potential as a systemic approach for the treatment of VS.
molecular weight	The protein has a predicted MW of 74.90 kDa. Due to furin cleavage site, the mature form migrates to 65-115 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Cynomolgus ADAM9 Protein 2774

protein

Size and concentration 100, 500µg and liquid
Form Liquid
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped with dry ice.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
A disintegrin and metalloproteinase 9 (ADAM9) is a member of the transmembrane ADAM family. It is expressed in different types of solid cancer and promotes tumor invasiveness. ADAM9 may be a prognostic marker for vestibular schwannomas (VS), and ADAM9 inhibition might have the potential as a systemic approach for the treatment of VS.
Protein names ADAM metallopeptidase domain 9
Gene names ADAM9,ADAM9
Mass 9541Da
Catalytic activity BINDING 347; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_note="catalytic"; /evidence="ECO:0000256\|PROSITE-ProRule:PRU00276"; BINDING 351; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_note="catalytic"; /evidence="ECO:0000256\|PROSITE-ProRule:PRU00276"; BINDING 357; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_note="catalytic"; /evidence="ECO:0000256\|PROSITE-ProRule:PRU00276"
Subellular location Membrane ; Single-pass type I membrane protein .
Target Relevance information above includes information from UniProt accession: A0A2K5X4X8
The UniProt Consortium

Data

Activity assay with Cynomolgus ADAM9 Protein

Measured by its ability to cleave a fluorogenic peptidesubstrate Mca-PLAQAV-Dpa-RSSSR-NH The specificactivity is > 1.0 pmol/min/ug.

The purity of Cynomolgus ADAM9 is greater than 90% as determined by SEC-HPLC.

SDS-PAGE gel of Cynomolgus ADAM9 Protein

Cynomolgus ADAM9 on Tris-Bis PAGE under reduced condition. The purity is greater than 90%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.