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Canine PD-1/PDCD1 Protein 2317

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Leu25-Val170
SKU: 2317parent Categories: , Tags: , , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

NP_001301026

express system

HEK293

product tag

C-hFc

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Programmed cell death protein 1, also known as PD-1 and CD279, is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.

molecular weight

The protein has a predicted MW of 43.00 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Canine PD-1/PDCD1 Protein 2317

Data

SPR with Canine PD-1/PDCD1 Protein
Canine PD-1, hFc Tag captured on CM5 Chip via proteinA can bind Human PD-L1, His Tag with an affinity constant of 0.696 µM as determined in SPR assay (Biacore T200).
ELISA with Canine PD-1/PDCD1 Protein
Immobilized Canine PD-1, hFc Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Human PD-L1, mFc Tag with the EC50 of 30.7ng/ml determined by ELISA (QC Test).
HPLC of Canine PD-1/PDCD1 Protein
The purity of Canine PD-1 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Canine PD-1/PDCD1 Protein
Canine PD-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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