Canine AFP Protein 3200

$300.00 – $1,000.00

Summary

Expression: HEK293
Pure: Yes (HPLC)
Amino Acid Range: Arg19-Val609

SKU: 3200parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	Q8MJU5
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	Alpha-fetoprotein is a shuttle protein that delivers nutrients through receptor-mediated endocytosis to embryotic cells. In adults, alpha-fetoprotein can shuttle drugs into alpha-fetoprotein receptor-positive myeloid-derived suppressor, regenerating and also cancer cells. Drugs with high-binding affinity to alpha-fetoprotein can activate or deplete targeted cells. Myeloid-derived suppressor cells activation leads to immune suppression that can be used for treating autoimmune diseases.
molecular weight	The protein has a predicted MW of 67.71 kDa. Due to glycosylation, the protein migrates to 68-70 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Canine AFP Protein 3200

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Alpha-fetoprotein is a shuttle protein that delivers nutrients through receptor-mediated endocytosis to embryotic cells. In adults, alpha-fetoprotein can shuttle drugs into alpha-fetoprotein receptor-positive myeloid-derived suppressor, regenerating and also cancer cells. Drugs with high-binding affinity to alpha-fetoprotein can activate or deplete targeted cells. Myeloid-derived suppressor cells activation leads to immune suppression that can be used for treating autoimmune diseases.
Protein names Alpha-fetoprotein (Alpha-1-fetoprotein) (Alpha-fetoglobulin)
Gene names AFP,AFP
Protein family ALB/AFP/VDB family
Mass 9615Da
Function Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin.
Catalytic activity BINDING 22; /ligand="Cu(2+)"; /ligand_id="ChEBI:CHEBI:29036"; /evidence="ECO:0000250"
Subellular location Secreted .
Tissues Plasma.
Structure Dimeric and trimeric forms have been found in addition to the monomeric form.
Post-translational modification Sulfated.
Target Relevance information above includes information from UniProt accession: Q8MJU5
The UniProt Consortium

Data

The purity of Canine AFP is greater than 95% as determined by SEC-HPLC.

Canine AFP on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.