Biotinylated Human BCMA/TNFRSF17 Trimer Protein 4580

$525.00 – $1,750.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Met1-Ala54

SKU: 4580parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
express system	HEK293
product tag	C-His-Avi
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by SEC-HPLC
background	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF).
molecular weight	The protein has a predicted MW of 29.5 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Biotinylated Human BCMA/TNFRSF17 Trimer Protein 4580
protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF).
Protein names
Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein) (CD antigen CD269)
Gene names
TNFRSF17,TNFRSF17 BCM BCMA
Mass
20165Da
Function
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Subellular location
Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Note=Perinuclear Golgi-like structures.
Tissues
Expressed in mature B-cells, but not in T-cells or monocytes.
Structure
Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6.
Domain
TOPO_DOM 1
Target Relevance information above includes information from UniProt accession: Q02223
The UniProt Consortium

ELISA with Biotinylated Human BCMA/TNFRSF17 Trimer Protein

Immobilized Human BAFF, hFc Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Human BCMA Trimer, His Tag with the EC50 of 11.1ng/ml determined by ELISA (QC Test).

Immobilized Anti-BCMA Antibody at 1µg/ml (100µl/Well) on the plate. Dose response curve for Biotunylated Human BCMA Trimer, His Tag with the EC50 of 1.9ng/ml determined by ELISA.

HPLC of Biotinylated Human BCMA/TNFRSF17 Trimer Protein

The purity of Biotunylated Human BCMA Trimer is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Biotinylated Human BCMA/TNFRSF17 Trimer Protein

Biotunylated Human BCMA Trimer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.