| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| product tag | C-His-Avi, also biotinylated |
Biotinylated Cynomolgus ACE2/ACEH Protein 4682
$525.00 – $1,750.00
Summary
- Expression: HEK293
- Functional: Yes (ELISA)
- Amino Acid Range: Gln18-Val739
Biotinylated Cynomolgus ACE2/ACEH Protein 4682
| protein |
|---|
| Size and concentration 100, 500µg and lyophilized |
| Form Lyophilized |
| Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Storage buffer Shipped at ambient temperature. |
| Purity > 95% as determined by Tris-Bis PAGE |
| target relevance |
|---|
| ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. |
| Protein names Angiotensin-converting enzyme (EC 3.4.-.-) |
| Gene names ACE2,ACE2 |
| Protein family Peptidase M2 family |
| Mass 9541Da |
| Subellular location SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000256|ARBA:ARBA00004221}. Cell membrane {ECO:0000256|PROSITE-ProRule:PRU01354}; Single-pass type I membrane protein {ECO:0000256|PROSITE-ProRule:PRU01354}. Cell projection, cilium {ECO:0000256|ARBA:ARBA00004138}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}. Secreted {ECO:0000256|ARBA:ARBA00004613}. |
| Target Relevance information above includes information from UniProt accession : A0A2K5X283 |
| The UniProt Consortium |
Data
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| Immobilized SARS-COV-2 Spike RBD, hFc Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Cynomolgus ACE2, His Tag with the EC50 of 0.28µg/ml determined by ELISA. |
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| The purity of Biotinylated Cynomolgus ACE2 is greater than 95% as determined by SEC-HPLC. |
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| Biotinylated Cynomolgus ACE2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.| pmid | title | authors | citation |
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Protocols
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Documents
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