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PD-1 (PDCD1)
PD-1 (PDCD1): PD-1 is an immune checkpoint receptor that plays a key role in regulating T-cell activity. Its expression in tumors is relevant for assessing the tumor microenvironment and immune evasion. Immunohistochemistry for PD-1 is used to evaluate potential responsiveness to immunotherapy, particularly in melanoma and lung cancer.
| target | type | reactivity | applications | ||||
|---|---|---|---|---|---|---|---|
| 6326 | PD-1 (PDCD1) | mouse monoclonal (ZM357) | human | IHC | |||
| 6327 | PD-1 (PDCD1) | rabbit monoclonal (ZR408) | human | IHC | |||
IHC with antibody [6326] : Formalin-fixed, paraffin-embedded human tonsil stained with anti-PD-1 antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of T-cells
IHC with antibody [6327] : Formalin-fixed, paraffin-embedded human tonsil stained with anti-PD-1 antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of germinal center T-cells
