ERK1 antibodies

ERK1 and ERK2 are crucial signaling proteins within the MAP kinase pathway, playing a central role in cell proliferation, differentiation, and survival. Their activation is often used as a marker for cellular responses to growth factors, stress, and other extracellular signals. Due to their widespread involvement in signaling pathways, ERK1 and ERK2 are frequently studied in Western blotting (WB) to assess changes in signal transduction under various experimental conditions.In addition to WB, antibodies against ERK1 and ERK2 available on your website can be used in immunofluorescence (IF) and immunohistochemistry (IHC) for visualizing their activation and localization within tissues or cells. The ability to detect phosphorylated forms of ERK1/2 provides insight into cellular responses at different stages of development, cancer progression, and other pathological conditions. The biological significance of ERK1 and ERK2 lies in their regulation of key cellular processes, including gene expression, cell cycle progression, and apoptosis, making them important markers in both normal physiology and disease research.