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Dermatopathology

Dermatopathology: IHC plays a key role in differentiating between various skin cancers, such as melanoma versus non-melanoma skin cancers, by identifying specific markers like S-100, HMB-45, and Melan-A. Inflammatory and infectious skin conditions also benefit from IHC, helping pathologists pinpoint the underlying causes and distinct cell types involved in skin disease.



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Formalin-fixed, paraffin-embedded human squamous cell carcinoma stained with anti-desmoglein-3 monoclonal antibody using peroxidase-conjugate and DAB chromogen. Note membranous staining of tumor cells
IHC with antibody [6159] : Formalin-fixed, paraffin-embedded human squamous cell carcinoma stained with anti-desmoglein-3 monoclonal antibody using peroxidase-conjugate and DAB chromogen. Note membranous staining of tumor cells
Human neuroblastoma stained with anti-Factor XIIIa antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of fibroblasts and macrophages.
IHC with antibody [6181] : Human neuroblastoma stained with anti-Factor XIIIa antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of fibroblasts and macrophages.
Formalin-fixed, paraffin-embedded human Langerhans cell histiocytosis stained with anti-langerin antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of tumor cells
IHC with antibody [6240] : Formalin-fixed, paraffin-embedded human Langerhans cell histiocytosis stained with anti-langerin antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of tumor cells