Mouse BCHE/Butyrylcholinesterase Protein 2485

$300.00 – $1,000.00

Summary

Expression: HEK293
Active: Yes (catalytic)
Amino Acid Range: Glu30-Leu603

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SKU: 2485parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	Q03311
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	Butyrylcholinesterase is a serine hydrolase biochemically related to the cholinergic enzyme acetylcholinesterase. It is capable of hydrolyzing esters of choline. Butyrylcholinesterase has unique enzymatic properties and is widely distributed in the nervous system, raising the possibility of its involvement in neural function.
molecular weight	The protein has a predicted MW of 66.13 kDa. Due to glycosylation, the protein migrates to 70-90 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Mouse BCHE/Butyrylcholinesterase Protein 2485

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Butyrylcholinesterase is a serine hydrolase biochemically related to the cholinergic enzyme acetylcholinesterase. It is capable of hydrolyzing esters of choline. Butyrylcholinesterase has unique enzymatic properties and is widely distributed in the nervous system, raising the possibility of its involvement in neural function.
Protein names Cholinesterase (EC 3.1.1.8) (Acylcholine acylhydrolase) (Butyrylcholine esterase) (Choline esterase II) (Pseudocholinesterase)
Gene names Bche,Bche
Protein family Type-B carboxylesterase/lipase family
Mass 10090Da
Function Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.
Catalytic activity BINDING 145..146; /ligand="substrate"; /evidence="ECO:0000250"
Subellular location Secreted .
Tissues Present in most cells except erythrocytes.
Structure Homotetramer; disulfide-linked. Dimer of dimers (By similarity).
Target Relevance information above includes information from UniProt accession: Q03311
The UniProt Consortium

Data

Activity assay with Mouse BCHE/Butyrylcholinesterase Protein

Measured by its ability to cleave Butyrylthiocholine. The specific activity is > 50000 pmoles/min/µg.

SDS-PAGE gel of Mouse BCHE/Butyrylcholinesterase Protein

Mouse BCHE on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.