HPLC of Biotinylated Human HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monom 2314

SDS-PAGE gel of Biotinylated Human HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVG 2314

Biotinylated Human HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer Protein 2314

$563.00 – $1,875.00

Summary

Expression: E.coli
Pure: Yes (HPLC)
Amino Acid Range: Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLVVVGAVGV peptide

SKU: 2314parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
express system	E.coli
product tag	C-His-Avi
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
molecular weight	The protein has a predicted MW of 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) same as Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Biotinylated Human HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer Protein 2314

protein

Size and concentration 100, 500µg and liquid
Form Liquid
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped with dry ice.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Protein names Major histocompatibility complex, class I, A
Gene names HLA-A,HLA-A
Protein family MHC class I family
Mass 41449Da
Target Relevance information above includes information from UniProt accession: A0A140T913
The UniProt Consortium

Data

HPLC of Biotinylated Human HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monom

The purity of Biotinylated Human HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Biotinylated Human HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVG

Biotinylated Human HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.