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Mouse PS20 Protein 3652

$315.00$1,050.00

Summary

  • Expression: E.coli
  • Pure: Yes (HPLC)
  • Amino Acid Range: Gln24-Pro211
SKU: 3652parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

Q9ESH5

express system

E.coli

product tag

N-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory infection in mice. Using ps20 knockout mice we provide evidence that intranasal MHV-1 infection results in increased lung viral titers in ps20(-/-) compared to ps20(/) mice. Roles for ps20 in regulating expression of neutrophil-specific chemotactic factors, thereby potentially modulating neutrophil migration, and in modulating neutrophil susceptibility to MHV-1 infection.

molecular weight

The protein has a predicted MW of 21.9 kDa. The protein migrates to 27-30 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Mouse PS20 Protein 3652

protein
Size and concentration
100, 500µg and liquid
Form
Liquid
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped with dry ice.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory infection in mice. Using ps20 knockout mice we provide evidence that intranasal MHV-1 infection results in increased lung viral titers in ps20(-/-) compared to ps20(/) mice. Roles for ps20 in regulating expression of neutrophil-specific chemotactic factors, thereby potentially modulating neutrophil migration, and in modulating neutrophil susceptibility to MHV-1 infection.
Protein names
WAP four-disulfide core domain protein 1 (Prostate stromal protein ps20) (ps20 growth inhibitor)
Gene names
Wfdc1,Wfdc1 Ps20
Mass
10090Da
Function
Has growth inhibitory activity.
Subellular location
Secreted .
Target Relevance information above includes information from UniProt accession: Q9ESH5
The UniProt Consortium

HPLC of Mouse PS20 Protein
The purity of Mouse PS20 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Mouse PS20 Protein
Mouse PS20 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmidtitleauthorscitation
We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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