Weight | 1 lbs |
---|---|
Dimensions | 9 × 5 × 2 in |
accession | Q9ESH5 |
express system | E.coli |
product tag | N-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory infection in mice. Using ps20 knockout mice we provide evidence that intranasal MHV-1 infection results in increased lung viral titers in ps20(-/-) compared to ps20(/) mice. Roles for ps20 in regulating expression of neutrophil-specific chemotactic factors, thereby potentially modulating neutrophil migration, and in modulating neutrophil susceptibility to MHV-1 infection. |
molecular weight | The protein has a predicted MW of 21.9 kDa. The protein migrates to 27-30 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Mouse PS20 Protein 3652
$315.00 – $1,050.00
Summary
- Expression: E.coli
- Pure: Yes (HPLC)
- Amino Acid Range: Gln24-Pro211
Mouse PS20 Protein 3652
protein |
---|
Size and concentration 100, 500µg and liquid |
Form Liquid |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped with dry ice. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
---|
The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory infection in mice. Using ps20 knockout mice we provide evidence that intranasal MHV-1 infection results in increased lung viral titers in ps20(-/-) compared to ps20(/) mice. Roles for ps20 in regulating expression of neutrophil-specific chemotactic factors, thereby potentially modulating neutrophil migration, and in modulating neutrophil susceptibility to MHV-1 infection. |
Protein names WAP four-disulfide core domain protein 1 (Prostate stromal protein ps20) (ps20 growth inhibitor) |
Gene names Wfdc1,Wfdc1 Ps20 |
Mass 10090Da |
Function Has growth inhibitory activity. |
Subellular location Secreted . |
Target Relevance information above includes information from UniProt accession: Q9ESH5 |
The UniProt Consortium |
![]() |
The purity of Mouse PS20 is greater than 95% as determined by SEC-HPLC. |
![]() |
Mouse PS20 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
pmid | title | authors | citation |
---|---|---|---|
We haven't added any publications to our database yet. |
relevant to this product |
---|
# | ||
---|---|---|
Please enter your product and batch number here to retrieve product datasheet, SDS, and QC information. |
Only logged in customers who have purchased this product may leave a review.
Reviews
There are no reviews yet.