ELISA with Mouse OX40/TNFRSF4/CD134 Protein 3397

Mouse OX40/TNFRSF4/CD134 Protein 3397

$210.00 – $700.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Val20-Pro211

SKU: 3397parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	P47741
express system	HEK293
product tag	C-His-Avi
purity	> 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC
background	Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation.
molecular weight	The protein has a predicted MW of 24.2 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per ug by the LAL method.

Mouse OX40/TNFRSF4/CD134 Protein 3397

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation.
Protein names Tumor necrosis factor receptor superfamily member 4 (OX40 antigen) (OX40L receptor) (CD antigen CD134)
Gene names Tnfrsf4,Tnfrsf4 Ox40 Txgp1
Mass 10090Da
Function Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity (By similarity).
Subellular location Membrane; Single-pass type I membrane protein.
Tissues Expressed in CD4(+) T-cells and in T-helper Th17 cells (at protein level).
Structure Interacts with TRAF2, TRAF3 and TRAF5.
Target Relevance information above includes information from UniProt accession: P47741
The UniProt Consortium

Data

ELISA with Mouse OX40/TNFRSF4/CD134 Protein

Immobilized Mouse OX40 Ligand, hFc Tag at 5µg/ml (100µl/Well) on the plate. Dose response curve for Mouse OX40, His Tag with the EC50 of 1.06µg/ml determined by ELISA.

HPLC of Mouse OX40/TNFRSF4/CD134 Protein

The purity of Mouse OX40 is greater than 90% as determined by SEC-HPLC.

SDS-PAGE gel of Mouse OX40/TNFRSF4/CD134 Protein

Mouse OX40 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.