Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | NP_067623 |
express system | HEK293 |
product tag | C-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | Glycoprotein A33 (GPA33) is also known as Cell surface A33 antigen, is a single-pass type I membrane protein which is expressed in normal gastrointestinal epithelium and in 95% of colon cancers. GPA33 The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily, which contains. GPA33 may play a role in cell-cell recognition and signaling. |
molecular weight | The protein has a predicted MW of 24.91 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Mouse GPA33/A33 Protein 3288
$225.00 – $750.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Leu22-Ile235
Mouse GPA33/A33 Protein 3288
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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Glycoprotein A33 (GPA33) is also known as Cell surface A33 antigen, is a single-pass type I membrane protein which is expressed in normal gastrointestinal epithelium and in 95% of colon cancers. GPA33 The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily, which contains. GPA33 may play a role in cell-cell recognition and signaling. |
Protein names Cell surface A33 antigen (Glycoprotein A33) |
Mass 35632Da |
Function May play a role in cell-cell recognition and signaling. |
Subellular location Membrane; Single-pass type I membrane protein. |
Tissues Expressed in normal gastrointestinal epithelium and in 95% of colon cancers. |
Post-translational modification N-glycosylated, contains approximately 8 kDa of N-linked carbohydrate. {ECO:0000269|PubMed:9245713}.; Palmitoylated. {ECO:0000269|PubMed:9245713}. |
Target Relevance information above includes information from UniProt accession: Q99795 |
The UniProt Consortium |
The purity of Mouse GPA33 is greater than 95% as determined by SEC-HPLC. |
Mouse GPA33 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
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