Cynomolgus NKG2A&CD94 Protein 3286

$315.00 – $1,050.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Pro94-Leu233(NKG2A) & Lys32-Ile179(CD94)

SKU: 3286parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	Q68VD2(NKG2A)&Q68VD4(CD94)
express system	HEK293
product tag	C-His, C-Flag
purity	> 95% as determined by Tris-Bis PAGE
background	The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK cell therapies.
molecular weight	The protein has a predicted MW of 17.01 kDa(NKG2A)&18.27 kDa(CD94). Due to glycosylation, the protein migrates to 25-35 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Cynomolgus NKG2A&CD94 Protein 3286

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK cell therapies.
Protein names NKG2A protein
Gene names nkg2A,nkg2A
Mass 26209Da
Subellular location Membrane ; Single-pass type II membrane protein .
Target Relevance information above includes information from UniProt accession: Q68VD2
The UniProt Consortium

ELISA with Cynomolgus NKG2A&CD94 Protein

Immobilized Cynomolgus NKG2A&CD94, His Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Anti-NKG2A Antibody, hFc Tag with the EC50 of 8.7g/ml determined by ELISA.

SDS-PAGE gel of Cynomolgus NKG2A&CD94 Protein

Cynomolgus NKG2A&CD94 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.